Trityl losartan

N-Trityl-2-(tritylsulfan­yl)aniline

The title compound, C(44)H(35)NS, is a derivative of amino-thio-phenol and possesses a protected S-triphenyl-methyl thio-ether and an N-triphenyl-methyl-amine functional group. The trityl groups show an anti orientation, with C-C-N-C and C-C-S-C torsion angles of -151.0 (3) and -105.3 (2)°, respectively. There is an intra-molecular N-H⋯S hydrogen bond.

Synthesis of N-Trityl-L-homoserine

L-Homoserine was tritylated via its silylated product with Me2SiCl2 or Ph2SiCl2 in 65-68% yield. Also N-Trt-L-methionine upon treatment with Mel and degradation of the resulting sulfonium salt with KOH yielded N-Trt-L-homoserine in 75% yield. Both routes provided N-Trityl-L-homoserine with identical physical data. In contrast to N-alkyloxycarbonyl-L-homoserine derivatives, N-Trt-L-homoserine sh...

Methyl 6-O-trityl-α-d-gluco­pyran­oside methanol disolvate

The asymmetric unit of the title compound, C26H28O6·2CH3OH, contains two independent methyl 6-O-trityl-α-d-gluco-pyran-oside mol-ecules and four methanol solvent mol-ecules. The rings of two methyl α-d-gluco-pyran-oside adopt chair conformations. In the crystal, extensive intra- and inter-molecular O-H⋯O and C-H⋯O hydrogen bonds link the mol-ecules into a three-dimensional supra-molecular archi...

Trityl radicals: spin labels for nanometer-distance measurements.

Spin labelling with trityls: to gather information about the structure and dynamics of trityl radicals, spin-labelled polymers were measured with pulsed electron-electron double resonance (PELDOR) and double-quantum coherence (DQC). This study demonstrates that trityl radicals have great potential as spin labels that eliminate some limitations of nitroxide spin labels.

Fenofibrate and losartan.